Diets Rich in Polyphenols Decrease Oxidative Stress

A study just released in the American Journal of Clinical Nutrition by Annuzzi and coworkers demonstrated that diets naturally rich in polyphenols positively influenced fasting and postprandial triglycerides and reduced oxidative stress. These effects may contribute to explain the favorable association of dietary polyphenols with cardiovascular risk.

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Increased Dietary Antioxidant Intake Associated With Improved Blood Pressure In Diabetic Individuals

A higher intake of dietary antioxidants measured as ORAC was associated with lower risks of hypertension. Read more…

New Study Shows Positive Relationship of Polyphenols & All-Cause Mortality

A new study published in The Journal of Nutrition by Zamora-Ros and coworkers provides further data on the importance of dietary polyphenolic consumption and health outcomes. The current study evaluated the relationship total urinary polyphenol excretion and total dietary polyphenol intake and all-cause mortality during a 12 year period among an older adult population. Total urinary polyphenol excretion was analyzed using the Folin-Ciocalteu assay which is a chemistry assay based upon a measure of antioxidant reactive compounds in the urine. A total of 807 participants were followed for a period of 12 years.  Participants in the highest one third for total urinary polyphenols experienced a 30% lower all-cause mortality than those in the lowest one third. In an earlier study by this same research group, high total urinary polyphenols were associated with a reduction in both systolic and diastolic blood pressure and with the prevalence of hypertension. The authors point out that polyphenol biomarkers have several advantages over dietary data collected using self-report methods in that they provide an objective measure that is independent of the biases and errors associated with self-report methods. The highest tertile of dietary intake of polyphenols was equivalent to approximately 10,800 micromoles TE/day. The full manuscript is available using the following link:

Ten Misconceptions about Antioxidants

“Owing to the polarity of views towards antioxidants, nutritional recommendation ranges from advice to increase antioxidant status in plasma to the notion that it is a useless measurement.”

• Opinions on antioxidants are highly polarized, leading to misunderstanding in the field.

• Specific antioxidants may have specific effects and side effects.

• With their pleiotropic modes of action, antioxidants should be considered bioactives


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Dietary Polyphenolics and Health; New review published discussing mechanisms of action beyond antioxidant effects

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